7脫氫膽固醇還原酶抗體說(shuō)明書
2021-11-25 14:16 作者:洛辰 來(lái)源:上海遠(yuǎn)慕生物試劑
【中文名稱】7脫氫膽固醇還原酶抗體
【英文名稱】Anti-DHCR7
【研究領(lǐng)域】腫瘤免疫學(xué)細(xì)胞凋亡
【抗體來(lái)源】Rabbit
【克隆類型】Polyclonal
【交叉反應(yīng)】Human,Mouse,Rat,Dog,Pig,Cow,Horse,GuineaPig,
【產(chǎn)品應(yīng)用】WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(石蠟切片需做抗原修復(fù))
notyettestedinotherapplications.
optimaldilutions/concentrationsshouldbedeterminedbytheenduser.
【分子量】57kDa
【細(xì)胞定位】細(xì)胞核細(xì)胞漿
【性狀】LyophilizedorLiquid111
【濃度】1mg/1ml
【免疫原】KLHconjugatedsyntheticpeptidederivedfromhumanAPI5
【亞型】IgG
【純化方法】affinitypurifiedbyProteinA
【儲(chǔ)存液】0.01MTBS(pH7.4)with1%BSA,0.03%Proclin300and50%Glycerol.
保存條件Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C.
【產(chǎn)品介紹】7脫氫膽固醇還原酶抗體Apoptosisinhibitor5(API5)isanantiapoptoticfactorwhichmayhavearoleinproteinassembly.7脫氫膽固醇還原酶抗體API5expressionisoftenupregulatedintumorcells,particularlyinmetastaticcells.ItisacriticaldeterminantofE2F1-inducedapoptosis,actingdownstreamofE2FtosuppressE2F-dependentapoptosiswithoutgenerallyblockingE2F-dependenttranscription.AlternateNames:AAC11;AAC11;Antiapoptosisclone11protein;API5;API5;API5like1;API5L1;Cellmigrationinducinggene8protein;Fibroblastgrowthfactor2interactingfactor2;FIF;MIG8;MIG8;MigrationinducingproteinMIG8;ProteinXAGL.