英文名稱    Epiphycan    

中文名稱    硫酸軟骨素蛋白多糖3抗體    

別    名    Dermatan sulfate proteoglycan 3; DSPG3; Epiphycan; epiphycan proteoglycan; EPYC; EPYC_HUMAN; Pg Lb; PG-Lb; PGLB; Proteoglycan-Lb; SLRR3B; Small chondroitin/dermatan sulfate proteoglycan.    

供 應 商   遠慕生物

研究領域    發育生物學  干細胞  糖蛋白      

抗體來源    Rabbit    

克隆類型    Polyclonal    

交叉反應    Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,     

產品應用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 硫酸軟骨素蛋白多糖3抗體（石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    35kDa    

細胞定位    細胞外基質 分泌型蛋白     

性    狀    Lyophilized or Liquid    

濃    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Epiphycan/DSPG3    

亞    型    IgG    

純化方法    affinity purified by Protein A    

儲 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

硫酸軟骨素蛋白多糖3抗體產品介紹    background:

DSPG3 is a 322 amino acid secreted protein that belongs to the small leucine-rich proteoglycan (SLRP) family. Expressed in cartilage, ligament and placenta, DSPG3 may have a role in bone formation and in establishing the ordered structure of cartilage through matrix organization. It has been suggested that DSPG3 regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins.

Function:
May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization.

Subcellular Location:
Secreted; extracellular space; extracellular matrix.

Tissue Specificity:
Cartilage, ligament, and placenta.

Post-translational modifications:
The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64.

Similarity:
Belongs to the small leucine-rich proteoglycan (SLRP) family.
SLRP class III subfamily.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.